Endocrine Abstracts

Thyroid cancer is the most common malignancy of the endocrine system. Papillary thyroid cancer is the most common thyroid malignancy worldwide and has a good prognosis. The prevalence of follicular thyroid cancer in endemic iodine deficiency regions is higher than in regions without iodine deficiency. However, it has been observed that the incidence of follicular thyroid cancer decreases and the incidence of papillary thyroid cancer increases after iodine prophylaxis. The Our ...

IntroductionMEN 2A is an autosomal dominant disease, a familial syndrome with a mutation at RET proto-oncogene. %25 of medullary thyroid carcinoma (MTC) is a part of MEN 2A. Herein, we presented a patient with MEN 2A who was found to be heterozygos for RET mutation cause of the association of MTC and papillary thyroid carcinoma (PTC) is very rare.Case63 year old patient was admitted to the endocrinology clini...

IntroductionMucopolysaccharidosis type 4A (Morquio 4A) is an autosomal recessive lysosomal storage disease caused by a mutation in the gene encoding galactosamine 6 sulphatase (GALNS). It’s main clinical features include short stature, skeletal dysplasia, cloudy cornea, hearing loss and dental anomalies. Herein, a case of Morquio 4A, a rare cause of short stature is presented.Case reportA 41 year old fem...

IntroductionImmunological side effects related with use of immune checkpoint inhibitors (ICIs) are named as immune-related adverse events (irAEs). irAEs include clinical pictures such as autoimmune thyroiditis, hypophysitis, primary adrenal insufficiency and autoimmune diabetes mellitus. Nivolumab is an anti-PD-1 (anti-programmed cell death-1) monoclonal antibody approved for the treatment of malignant melanoma, advanced non-small cell lung cancer and ad...

Objective11-Beta Hydroxylase deficiency (11ß0HD) is a rare form of congenital adrenal hyperplasia, resulting in glucocorticoid deficiency, virilization and hypertension. In the literature, there are rare case reports of successful pregnancy in a patient with genetically confirmed classic 11ß0HD.CaseOur patient, now age 31, was diagnosed at birth with ambiguous genitalia. There was no family history ...

AimLockdown order during COVID-19 pandemic caused a sedentary life-style and disruptions in eating and sleeps patterns of obese patients. In this study, it is planned to evaluate the clinical and metabolic effects of this period on obese patients.MethodsThis study included 44 obese patients who were followed up in Endocrinology and Metabolic Diseases Clinic of Karadeniz Technical University. In this study, me...